• Cutting-Edge
    Clinical Trials

Every therapy, drug or approach that is in place today to treat cancer had its start in a clinical trial. American Oncology Partner practices bring innovative treatment options to patients, close to home. By partnering with Sarah Cannon, a global leader in offering community-based clinical trials, we offer clinical trial options to patients across several locations within AON’s network of oncology practices.

Clinical Trial researcher placing test tube in holder.

Why participate in clinical trials?

Clinical trials are designed to evaluate the effectiveness of new treatment interventions. The objective of these clinical trials is to test new therapies in patients who have cancer. Patients participate in clinical trials for several reasons, including:

  • The potential to benefit from a new drug or treatment procedure
  • Improved management of symptoms resulting from treatment of cancer
  • The opportunity to directly contribute to improving the understanding of how to treat a cancer and ultimately, benefit other patients

Patients who participate in clinical trials receive either a promising new treatment or the best available conventional treatment. If a new treatment option is proven to work, patients who are participating in the clinical trial will be among the first to benefit. While there is no guarantee that any treatment will be successful, clinical trials have been proven to offer some of the most effective cancer treatments currently available today.

Talk to your doctor to discuss your clinical trial options.

Search for a Clinical Trial

Cancer Type


Line of Therapy


Colon and Rectal Cancer

BESPOKE Study of ctDNA Guided Therapy in Colorectal Cancer

20140346 RECITE

Colon and Rectal Cancer, Pancreatic Cancer, Hematology and Blood Disorders

A phase 3 Randomized Placebo-controlled Double-blind Study of Romiplostim for the Treatment of Chemotherapy-induced Thrombocytopenia in Patients Receiving Oxaliplatin-based Chemotherapy for Treatment of Gastrointestinal, Pancreatic, or Colorectal Cancer

20170543 CodeBreak 100

Biliary Cancer, Brain Cancer, Breast Cancer, Head and Neck Cancer, Kidney Cancer, Liver Cancer, Melanoma, Ovarian and Endometrial Cancer, Pancreatic Cancer, Prostate Cancer

A Phase 1/2, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of AMG 510 Monotherapy in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation and AMG 510 Combination Therapy in Subjects With Advanced NSCLC With KRAS p.G12C Mutation (CodeBreak 100)



A Randomized, Double-blind Study Evaluating the Efficacy, Safety, and Immunogenicity of ABP 206 Compared with Opdivo (Nivolumab) in Subjects with Treatment-naïve Unrespectable or Metastatic Melanoma

61186372EDI1001 CHRYSALIS

Lung Cancer

A Phase 1, First-in-Human, Open-Label, Dose Escalation Study of JNJ-61186372, a Human Bispecific EGFR and cMet Antibody, in Subjects With Advanced Non-Small Cell Lung Cancer

849-001 (RM 615) KRYSTAL-1

Lung Cancer, Colon and Rectal Cancer, Pancreatic Cancer

A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation KRYSTAL-1

849-010 (GI 311) KRYSTAL-10

Colon and Rectal Cancer

A Randomized Phase 3 Study of MRTX849 in Combination With Cetuximab Versus Chemotherapy in Patients With Advanced Colorectal Cancer With KRAS G12C Mutation With Disease Progression On or After Standard First-Line Therapy


Prostate Cancer, Supportive Care

A Randomized, Double-Blind, Placebo-Controlled Phase II Study of Oxybutynin Versus Placebo for the Treatment of Hot Flashes in Men Receiving Androgen Deprivation Therapy

AB-106-G208 (PRO 23) TRUST-II

Lung Cancer, Solid Tumors

A Single-Arm, Open-Label, Multicenter Phase 2 Study to Evaluate the Efficacy and Safety of Taletrectinib in Patients With Advanced or Metastatic ROS1 Positive NSCLC and Other Solid Tumors