D926NC00001 (LUN 512) AVANZAR
A Phase III, Randomised, Open-label, Multicentre, Global Study of Datopotamab Deruxtecan (Dato-DXd) in Combination With Durvalumab and Carboplatin Versus Pembrolizumab in Combination With Platinum-based Chemotherapy for the First-line Treatment of Patients With Locally Advanced or Metastatic NSCLC Without Actionable Genomic Alterations
Cancer Types: Lung CancerLines of Therapy: 1st Line Metastatic and Locally Advanced
More details: https://clinicaltrials.gov/study/NCT05687266?term=D926NC00001&rank=1
Practices offering this clinical trial:
EC-120888 (LUN 437)
A Randomized Prospective Trial of Adjuvant Chemotherapy in Patients With Completely Resected Stage I or IIA Non-squamous Non-Small Cell Lung Cancer Identified as High or Intermediate Risk by a 14-Gene Prognostic Assay
Cancer Types: Lung CancerLines of Therapy: Adjuvant
More details: https://clinicaltrials.gov/ct2/show/NCT01817192
Practices offering this clinical trial:
EZH-302 (LYM 170) SYMPHONY-1
A Phase 1b/3 Double-blind, Randomized, Active-controlled, 3-stage, Biomarker Adaptive Study of Tazemetostat or Placebo in Combination With Lenalidomide Plus Rituximab in Subjects With Relapsed/Refractory Follicular Lymphoma
Cancer Types: LymphomaLines of Therapy: 2nd Line Metastatic, Other
More details: https://clinicaltrials.gov/ct2/show/NCT04224493?term=EZH-302&draw=2&rank=1
Practices offering this clinical trial:
J2J-MC-JZLH (BRE 402) EMBER-4
A Randomized, Open-Label, Phase 3 Study of Adjuvant Imlunestrant vs Standard Adjuvant Endocrine Therapy in Patients Who Have Previously Received 2 to 5 Years of Adjuvant Endocrine Therapy for ER+, HER2- Early Breast Cancer With an Increased Risk of Recurrence
Cancer Types: Breast CancerLines of Therapy: Adjuvant
More details: https://clinicaltrials.gov/ct2/show/NCT05514054?term=j2j-mc-jzlh&draw=2&rank=1
Practices offering this clinical trial:
JZP598-303 (BRE 430)
A Study Comparing the Efficacy and Safety of Zanidatamab to Trastuzumab, Each in Combination With Physician's Choice Chemotherapy, for the Treatment of Participants With Metastatic HER2-positive Breast Cancer
Cancer Types: Breast CancerLines of Therapy: 2nd Line Metastatic, 3rd Line + Metastatic
More details: https://clinicaltrials.gov/study/NCT06435429?term=jzp598-303&rank=1
Practices offering this clinical trial:
PRESERVE-003 (LUN 514)
Phase 3, Two-stage, Randomized Study of ONC-392 Versus Docetaxel in Metastatic Non-Small Cell Lung Cancers That Progressed on PD-1/PD-L1 Inhibitors
Cancer Types: Lung CancerLines of Therapy: 2nd Line Metastatic
More details: https://classic.clinicaltrials.gov/ct2/show/NCT05671510?term=Phase+3%2C+Two-stage%2C+Randomized+Study+of+ONC-392+Versus+Docetaxel+in+Metastatic+Non-Small+Cell+Lung+Cancers+that+Progressed+on+PD-1%2FPD-L1+Inhibitors&draw=2&rank=1
Practices offering this clinical trial:
S1823
A Prospective Observational Cohort Study to Assess miRNA 371 for Outcome Prediction in Patients With Newly Diagnosed Germ Cell Tumors
Cancer Types: TesticularLines of Therapy: Other
More details: https://clinicaltrials.gov/ct2/show/NCT04435756
Practices offering this clinical trial:
S1914
A Randomized Phase III Trial of Induction/Consolidation Atezolizumab (NSC #783608) + SBRT Versus SBRT Alone in High Risk, Early Stage NSCLC
Cancer Types: Lung CancerLines of Therapy: 1st Line Metastatic and Locally Advanced
More details: https://clinicaltrials.gov/ct2/show/NCT04214262?term=s1914&draw=2&rank=1
Practices offering this clinical trial:
TT420C2308 (GI 356)
Study of Tinengotinib VS. Physician's Choice a Treatment of Subjects With FGFR-altered in Cholangiocarcinoma (FIRST-308)
Cancer Types: Biliary CancerLines of Therapy: 2nd Line Metastatic, 3rd Line + Metastatic
More details: https://clinicaltrials.gov/study/NCT05948475?term=NCT05948475&rank=1
Practices offering this clinical trial:
TTX-030-003 (GI 361)
An Open-Label Multicenter 3-Arm Randomized Phase 2 Study to Assess the Efficacy and Safety of TTX-030 and Chemotherapy With or Without Budigalimab, Compared to Chemotherapy Alone, for the Treatment of Patients not Previously Treated for Metastatic Pancreatic Adenocarcinoma
Cancer Types: Pancreatic CancerLines of Therapy: 1st Line Metastatic and Locally Advanced
More details: https://classic.clinicaltrials.gov/ct2/show/NCT06119217
Practices offering this clinical trial:
ZEN003694-201 (GU 200)
A Randomized Phase 2b Study of ZEN003694 in Combination With Enzalutamide Versus Enzalutamide Monotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer
Cancer Types: Prostate CancerLines of Therapy: 1st Line Metastatic and Locally Advanced
More details: https://clinicaltrials.gov/ct2/show/NCT04986423?term=ZEN003694-201&draw=2&rank=1
Practices offering this clinical trial: